Therapy with Nasal Insufflation...the more efficient NHF Therapy

From the clinic

intensiv or clinical

as well as in homecare

adult COPD-/ILD- or OSA-patients,

neonatals, IRDS-/BPD-or Bronchiolitis- patients,

prematures, neonatals and infant OSA-patients

the TNI-systems guarantee

an exact regulated flow ratea stable FiO₂

an effective humidity management

TNI^® - efficient therapy follows patients

Our product range:

Method and Effects

During the therapy, a constant warm and humidified air flow, if required combined with oxygen, is applied into the nose of the patient by means of thin nasal prongs (applicator). This always leads to an improved ventilation. The Therapy with Nasal Insufflation has a high level of therapy acceptance and excellent therapeutic success.

A number of attestations and clinical findings show that the Therapy with Nasal Insufflation actually

supports insufficient breathing and shows a clinical benefit
which leads to improved elimination of CO_2,
reduces the functional dead space,
supports and relieves the respiratory pump

The findings especially recommend the Therapy with Nasal Insufflation as a therapy option for a further reduction of a mechanical respiratory support or for patients who do not accept the usual mask ventilation.

Improved Ventilation by the Help of

Benefits for Doctors & Patients

Medical brochure

Expand your therapeutic options

Procedure

Publications / Studies

Below, you will find a selection of current publications on the Nasal High Flow therapy.

Adults

Jens Bräunlich, Dominic Dellweg, Andreas Bastian, Stephan Budweiser, Winfried Randerath, Dora Triché, Martin Bachmann, Christian Kähler, Abdel Hakim Bayarassou, Irmhild Mäder, Jens Geiseler, Norbert Köhler, David Petroff, Hubert Wirtz
Nasal high-flow versus noninvasive ventilation in patients with chronic hypercapnic COPD
International Journal of Chronic Obstructive Pulmonary Disease 2019:14 1411–1421
Published: 5 July 2019

Helene Vogelsinger, Michael Halank, Silke Braun, Heinrike Wilkens, Thomas Geiser, Sebastian Ott, Armin Stucki and Christian M. Kaehler, 2017
Efficacy and safety of nasal high-flow oxygen in COPD patients
BMC Pulmonary MedicineBMC series – open, inclusive and trusted 201717:143
Published: 17 November 2017

Bräunlich, J., Köhler, M., Wirtz, H., 2016.
Nasal highflow improves ventilation in patients with COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 11, 1077–1085. doi:10.2147/COPD.S104616

Bräunlich, J., Nilius, G., 2016. Nasaler Highflow (NHF): Eine neue Therapiealternative zur Behandlung der respiratorischen Insuffizienz. Pneumologie 70, 49–54. doi:10.1055/s-0041-110286

Bräunlich, J., Wirtz, H., 2015. Nasaler Highflow – Bessere Alternative der Sauerstoffapplikation bei schwerer Hypoxie? Dtsch Med Wochenschr 140, 1823–1826. doi:10.1055/s-0041-107889

Bräunlich, J., Seyfarth, H.-J., Wirtz, H., 2015
Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD:
a preliminary report. Multidiscip. Respir. Med. 10, 27. doi:10.1186/s40248-015-0019-y

Bräunlich, J., Beyer, D., Mai, D., Hammerschmidt, S., Seyfarth, H.J., Wirtz, H., 2013. Effects of nasal high flow on ventilation in volunteers, COPD and idiopathic pulmonary fibrosis patients. Respiration 85. doi:10.1159/000342027

McGinley, B.M., Patil, S.P., Kirkness, J.P., Smith, P.L., Schwartz, A.R., Schneider, H., 2007:
A Nasal Cannula Can Be Used to Treat Obstructive Sleep Apnea
Am. J. Respir. Crit. Care Med. 176, 194–200. doi:10.1164/rccm.200609-1336OC

Nilius, G., Franke, K.-J., Domanski, U., Rühle, K.-H., Kirkness, J.P., Schneider, H., 2013. Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure. Adv. Exp. Med. Biol. 755, 27–34. doi:10.1007/978-94-007-4546-9_49180

Nilius, G., Wessendorf, T., Maurer, J., Stoohs, R., Patil, S.P., Schubert, N., Schneider, H., 2009. Predictors for Treating Obstructive Sleep Apnea With an Open Nasal Cannula System (Transnasal Insufflation). ResearchGate 137, 521–8. doi:10.1378/chest.09-0357

Plattner, L., Vogelsinger, H., Janschek, E., Kähler, C.M., 2013. Highflow-Sauerstofftherapie – Auswirkung auf die Blutgase bei schwerer COPD. Pneumologie 67, P35. doi:10.1055/s-0033-1345073

Vogelsinger, H., Halank, M., Wilkens, H., Geiser, T., Braun, S., Plattner, L., Janschek, E., Ott, S., Stucki, A., Kaehler, C.M., 2013. Highflow-Sauerstoffttherapie bei hyperkapnischen COPD-Patienten: optimiertes Sauerstoffangebot – Daten aus der STIT-2-Studie. Pneumologie 67, P40. doi:10.1055/s-0033-1345078

Infants

McGinley, B., Halbower, A., Schwartz, A.R., Smith, P.L., Patil, S.P., Schneider, H., 2009. Effect of a high-flow open nasal cannula system on obstructive sleep apnea in children. Pediatrics 124, 179–188. doi:10.1542/peds.2008-2824

Effects of high-flow transnasal insufflation compared with CPAP and spontaneous breathing on pressure amplitude and mean pressure in patients with IPF and COPD (2010)

Einfluss der transnasalen Insufflation TNI^® auf Atemdruckamblitude & Atemmitteldruck im Vergleich zu Spontanatmung und CPAP (2010)

Effect of an Open Nasal Cannula System (TNI^®) in hypercapnic respiratory failure in COPD patients (2009)

Einfluss der transnasalen Insufflation (TNI^®) auf Atemdruckamplitude und Atemmitteldruck im Vergleich zu Spontanatmung und CPAP beim Lungengesunden (2009)

Treatment of Sleep-Disordered Breathing in Chronic Obstructive Pulmonary Disease with Nocturnal Nasal Insufflation (2007)

Sommnologie 2007:
072: Multicenterstudie zur Wirksamkeit der transnasalen Insufflation (TNI^®) bei leichter bis mittelgradiger pharyngealer Obstruction und Schlafapnoe

Cleven, J., Vogelsinger, H., Ott, S., Geiser, T., Halank, M., Kähler, C.M., 2012. Effekt transnasaler “High-Flow-Sauerstoff-Insufflation” bei Patienten mit schwerer COPD. Pneumologie 66, P13. doi:10.1055/s-0032-130

Further recommendations:

High-Flow Oxygen through Nasal Cannula
in Acute Hypoxemic Respiratory Failure (Jean-Pierre Frat) 2015

Nasal High-Flow versus Venturi Mask Oxygen Therapy after Extubation (S.M. Maggiore) 2014

Clinical evidence on high flow oxygen therapy and active humidification in adults (C. Gotera) 2013

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